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enzymatic cleavage releases 4-methylumbelliferone
which can be removed by hydrogenolysis to reveal the free amine for conjugation
Fmoc-Thr(α(1-2)Mannobiose)-OH (Peracetate)
α-GalNAc-C4-COOCH3
Colecalciferol-d3
GP100095: RPB1 CTD(1615-1621-Lys)-Tn(1619) Pack Size:0.5 mg enzymatic cleavage releases 4-methylumbelliferoneC46H73N11O18 1068. 1 DNA directed RNA polymerase II (Pol II) subunit RPB1 contains a Carboxy Terminal Domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity. The CTD Nonconsensus Repeat, Tyr Ser Pro Thr Ser Pro Ser, is heavily modified by phosphorylation, glycosylation and proline isomerization. The CTD acts as a tether to bring into close proximity the machinery necessary to synthesize and process
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