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developed a set of genetic manipulation methods targeting over 140 non-model gut microorganisms across 5 phyla, including Firmicutes

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Protein interacting with C kinase 1 (PICK1), which binds to the GluR2 via the PDZ domain [37], provides binding domains for PKC and glutamate receptor-interacting proteins (GRIP), which ultimately helps in phosphorylation and the internalization of AMPAR [37,38,39]

The synergy claim is mechanistic, derived from the three peptides acting on different nodes of overlapping pathways (VEGF, NF-kB, ECM remodeling)

The expression of the UT-B1 isoform is ubiquitous being found in numerous human tissues in addition to erythrocytes