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VPM will be useful in probing the mechanism of EBV lytic reactivation and may have therapeutic application

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Furthermore, we show that targeting mitochondrial metabolism, particularly by inhibiting Complex I, sensitizes CRC cells to 5FU, resulting in delayed tumour growth and prolonged survival in preclinical models

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In vitro experiments have shown that GSH deficiency induced by either the siRNA approach or pharmacological inhibition of the GCL rate-limiting enzyme decreases GSH biosynthesis and escalates oxidative stress in cultured hepatocytes

4 Formulation factors Product-related factors differ between biologics as well as for an approved therapeutic and its biosimilar, 4 especially when it comes to formulations