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Despite the effectiveness of immune checkpoint inhibitors (ICIs), some patients do not respond to them and there may be adverse inflammatory reactions similar to autoimmune diseases, promoting research into combination therapies for cancer treatment [144]

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Healthy people typically have selenium serum levels between 80 and 120 g/L [1]

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The transition from episodic to chronic migraine involves changes in nociceptive thresholds and central sensitization, driven by factors such as high frequency of migraine attacks, overuse of acute medications, obesity, stress, female sex, psychiatric conditions, and low socioeconomic status (34)