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The FDA prescribing information for these agents lists common adverse effects including nausea, vomiting, diarrhea, constipation, and abdominal pain, but does not include blood clots among recognized risks

8,20 However, this strategy carries the risk of losing therapeutic effectiveness due to the accumulation of drug carriers in unintended sites, such as the liver

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Randomized, controlled clinical trial of zinc supplementation to prevent immunological failure in HIV-infected adults

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* Correspondence: Xinyu Liu, [email protected]