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Various CVOT trials, such as the SELECT, SUSTAIN, and SOUL trials, have demonstrated varying effects on heart diseases over the years [13,39,46]
2020;11:467 Scotton WJ, Botfield HF, Westgate CS, Mitchell JL, Yiangou A, Uldall MS, et al
GLP-1RAs and CVOTs Available GLP-1RAs (except for exenatide twice daily) have been examined in multicentre, double-blinded, randomised, placebo-controlled cardiovascular (CV) outcomes trials (CVOTs)
Intravenous and non-oral formulations Parenteral drugs bypass the gastrointestinal tract entirely and are not subject to any GLP-1-mediated absorption effect
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