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The parenteral administration also halts the progression of neurological damage associated with B12 deficiency, but the complete improvement of the condition may depend on the severity and extent of the deficiency.[12][13] Contraindications & Precautions Cyanocobalamin is contraindicated in those with hypersensitivity to cobalt moiety or cobalamin molecule due to the risk of anaphylaxis.[21] Warnings: The use of cyanocobalamin is warned in patients with early Lebers disease as there have been reports of severe and swift optic atrophy with its administration

This is accurate if the concentration is 10,000mcg/mL

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In fact, clinical and experimental studies show that methylcobalamin can improve nerve conduction and reduce pain levels in neuropathic patients

Common doses are 200 to 500 micrograms once or twice a day, for 2 to 6 weeks

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