Insulin-like growth factor (IGF), prolactin, sex hormone-binding globulin (SHBG), DHEA (dehydroepiandrosterone), testosterone, and thyroid hormones must also be optimized
Patients often face potentially high costs even with partial coverage for the branded semaglutide versions
They may feel out of date on the latest research, dosing instructions, or strategies for managing side effects
Edwards CM, Stanley SA, Davis R, et al
Liraglutide improves insulin sensitivity in high fat diet induced diabetic mice through multiple pathways
Practical mitigation strategies include slower dose titration, ensuring adequate vitamin C and protein intake (both essential for collagen synthesis), monitoring skin integrity at regular intervals, and discussing collagen-supportive skincare with your dermatology provider if changes become noticeable