The investigators reported sustained increases in growth velocity over 8 years of mecasermin treatment, with a favorable safety profile in this pediatric population [2]
We sought public comments on our proposed design, evaluation, data collection methods, and research questions
Adding exogenous IGF1 LR3 provides more direct receptor start beyond what endogenous IGF-1 production achieves
A short trial can reveal whether a platforms promises hold up under real conditions
The improved sporting performance, reported over several weeks of testing, appears to be dosage dependent
In addition, since multiple factors underlie the complex pathogenesis of Hg toxicity including genetic and environmental factors, their interactions could also be contributing to the associations found in our study