doi:10.1128/mcb.22.10.3373-3388.2002
In general, the A1C lowering capacity is greatest for metformin and sulfonylureas (average 12%), next greatest for GLP-1 agonists and thiazolidinediones (average 11.5%), and least for meglitinides, dipeptidyl peptidase 4 (DPP-4) inhibitors, alpha-glucosidase inhibitors (AGIs), and colesevelam (average 0.51%)
Diabetes Care 40 , 136154 (2017)
GSH or GABA concentrations equal to 0 were interpreted as evidence of failure to fit and those data points were excluded from further analysis (SM1 n=0, Thal n=0, mPFC n=2, SMA n=2)
indicated that 30 g/d glutamine for 6 weeks substantially decreased FBS and Hb A1c in patients with T2DM
Yes, switching between these medications is possible but should only be done under the supervision of a healthcare provider