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PMCID: PMC8622150

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Semaglutide 2.4 mg weekly, assessed in 17,604 individuals with body mass index (BMI) 27 kg/m and cardiovascular disease (CVD), resulted in 8.51% weight loss at 104 weeks and a 20% reduction in nonfatal Myocardial Infarction (MI), stroke, and cardiovascular death

Finally, in vitro work has looked at cellular signaling downstream of 3-AR engagement, providing mechanistic support for the lipolysis-without-hyperglycemia profile that investigators consistently observe

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In certain cases, Wegovy may also be considered for individuals 18 and older who meet specific health criteria