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The key difference between medication-related changes and IBS flares is that medication-induced symptoms typically peak in weeks 1-3 and improve with dose titration, whereas IBS symptoms fluctuate based on triggers like stress, food sensitivities, and gut microbiota shifts

Studies with long follow-up are required to confirm the cardiovascular safety

The weight loss is tied to the temporary conditions created by the medication

Javed et al

Toujeo specifically enters the picture when a patient needs basal insulin and either has already tried and failed GLP-1 therapy, has a contraindication to GLP-1 drugs, has Type 1 diabetes, or has very advanced Type 2 diabetes with negligible beta cell function

Thigh injections work particularly well for people who find abdominal injections uncomfortable, those who prefer to inject while sitting, and individuals who want maximum site rotation options