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However, a dysregulated increase in the level of these free radicals, as seen in mitochondrial diseases, can result in oxidative damage by overwhelming the cellular antioxidant defence mechanism, of which glutathione is the principal component [4]

NRF2 is reported to have suppressive effects on the lipogenic pathway via inhibiting the activity of LXR 64,70 , a transcription factor that supports lipid synthesis

Lifestyle Changes: Prioritize adequate sleep, and regular exercise to support your body's natural production of glutathione and collagen

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