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That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it
Yes, B12 injections are safe and often prescribed when oral supplementation isnt effective [*]
Long-term low B12 can drive elevated homocysteine and contribute to megaloblastic or pernicious anemia
Clinics often combine these in an IM injection as one component of a broader Weight Management plan
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Tests like vitamin B12 levels and blood counts help guide the dosing
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