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Gody, D., Herbut, P

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Most formulations are administered via subcutaneous injection (except oral semaglutide), typically weekly or daily depending on the specific medication, with dosing gradually increased over several weeks to minimize gastrointestinal side effects and optimize therapeutic response

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Research has documented lower circulating MOTS-c in patients with obesity, type 2 diabetes, and insulin resistance, and higher levels in populations with healthy metabolic aging