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It is deliberately membrane-permeable, which is what lets it get inside cells and act on an intracellular enzyme

Milestones in digestive system cancer organoid development Although organoid technology has been explored for several decades, its broad application in digestive system cancer research gained momentum more recently

Targeting HDACs with HDACi might have potential for treatment of neurological disorders such as Huntington's disease, Alzheimer's disease, amyotrophic lateral sclerosis, seizure disorders, spinal muscular atrophy, Rett syndrome, stroke, Fragile X syndrome, and Rubinstein-Taybi syndrome (Saha and Pahan, 2005)

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