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Making unclear that their drugs are untested and unregulated might lead to potential harm. The researchers hope their findings inform regulatory policy changes for compounded drugs advertising to protect consumers, said Joseph Ross, MD, MHS, professor of medicine (general medicine) at YSM and of public health (health policy and management) at the Yale School of Public Health and a member of the team

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Possible mechanisms by which SGLT-2 inhibitors exert their cardiorenal benefits include reductions in insulin resistance, inflammation, oxidative stress [38], and the risk of albuminuria [39,40]