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By harnessing the ability to modulate these erasers, it is anticipated that novel therapeutic strategies can be devised to regulate lactylation-associated diseases, including cancer, in the foreseeable future

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The authors explicitly note that these AE/SAE rates are broadly comparable to pivotal programs for weekly semaglutide (high overall AE rates, ~10% SAE) and tirzepatide (~80% AE rates, ~57% SAE), and they argue tolerability can be further improved with a more conservative titration scheme in Phase 3

Patients may experience side effects such as gastrointestinal discomfort, and certain populations, such as those with pancreatitis or severe gastrointestinal disorders, may not be suitable candidates

*FOR GET THE FLU SHOT AT THE SAME TIME: The Centers for Disease Control and Prevention

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