10.1146/annurev.arplant.47.1.127 77 MasaiE.IchimuraA.SatoY.MiyauchiK.KatayamaY.FukudaM
Because human data are limited, any influence on malignancy-related processes remains an area requiring significant further research one reason the compound is restricted to experimental settings
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The synergy rationale extrapolates from: (1) documented synergy between GHRH and various GHRPs (particularly GHRP-6) across multiple species and systems, (2) individual characterization of CJC-1295 No DAC showing 49-fold potency enhancement, (3) individual characterization of Ipamorelin showing comparable potency to GHRP-6 but with superior selectivity, and (4) established mechanistic principles of complementary receptor pathway activation
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