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Semaglutide works by activating GLP-1 receptors in the brain, pancreas, and gastrointestinal tract to reduce appetite, slow gastric emptying, and improve metabolic function

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Alternative GLP-1 Options If Heartburn Persists If tirzepatide-related heartburn doesn't respond to management strategies within 46 weeks, switching to semaglutide may be worth exploring

Chronic inflammation or lack of oxygen in tissues can irritate nerves