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Eat Weight Disord 26(8):24292441 Staiger H, Machicao F, Fritsche A, Haring HU (2009) Pathomechanisms of type 2 diabetes genes

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49 Even more interestingly, patients who showed an improvement in endothelial function after intraarterial infusion with vitamin C (showing an evidence of endothelial dysfunction caused by increased oxidative stress), had a worse prognosis as compared with patients with a low or no vitamin C effects

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Treatments can be grouped in 3 categories: conservative, office-based, and surgical