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doi: 10.1128/jb.182.15.4348-4351.2000
As reduced appetite and a change in sensitivity to texture and flavor reshape how consumers experience food and drink, formulators are facing new challengesfrom digestive tolerance limits and satiety to protein mouthfeel offnotes and the lingering sweetness profiles of naturederived sweeteners like stevia
Radovits BJ, et al
In an animal study, inhibition of the NF-B pathway led to a significant reduction in the expression of serum proinflammatory cytokines, including IL-6, IL-1 and TNF-, as well as an increase in the expression of the tight junction proteins occludin and ZO-1, thereby improving the function and structure of the intestinal mucosa
(In fact, in 2020, Ozempic was also approved as a treatment to reduce the risks of life-threatening cardiovascular events like stroke and heart attack in those with type 2 diabetes and a history of heart disease.) More recently, in January 2025, the FDA added another indication to the list when it approved Ozempic as a treatment to reduce the risk of major kidney events and worsening kidney disease in those with type 2 diabetes and chronic kidney disease
