Approved in November 2023, Zepbound represents a dual agonist approach to metabolic regulation, targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors
Retatrutide is not TGA-approved for therapeutic use in Australia
Chronic hypoxia for 7 or 14 d, but not 1 or 3 d, resulted in alpha-synuclein hyperphosphorylation at serine129 (-Syn p-S129) and protein aggregation, hippocampal neurodegeneration, and cognitive deficits, whereas the latter could be prevented by alpha-synuclein knockdown or an administered short peptide competing at -Syn S129
When the liver is functioning optimally, your entire metabolic system benefitsmaking weight-loss efforts feel less like an uphill battle
Side effects vary by drug and dosage, and this is not a complete list of side effects
A cross-sectional study in the Journal of Sexual Medicine (N=620 women with obesity) found that a 10-unit reduction in BMI was associated with a 1.3-point improvement on the Female Sexual Function Index (FSFI total score range 2 to 36) [11]
