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The traditional classification of microglial phenotypes into binary M1 (pro-inflammatory) and M2 (anti-inflammatory/neuroprotective) categories has provided a useful conceptual framework, though it is increasingly recognized as an oversimplification of their functional diversity (Figure 5)

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Patent Type Assay Compound : Active substance tested and measured in an assay to determine its activity or effect on a specific target

In addition, pharmacological innovations address BBRs low oral bioavailability through four core methods: (1) Botanical synergists (e.g., silymarin, isoliquiritigenin) amplifying therapeutic effects

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N-Acetyl Cysteine naturally contains sulfur and may produce a noticeable sulfur-like scent in supplements