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Although these strategies require further clinical validation, this work marks a critical step toward developing effective treatments for rare liver tumors

As SR-BI is a well-known player in reverse cholesterol transport, hepatic cholesterol uptake and is modulated by ovarian hormone estradiol, along with being regulated via IDO1 under inflammation, in the present study, we aim to elucidate the relationship between ovarian hormone deprivation, hepatic inflammation, IDO1, Trp-catabolism and cholesterol homeostasis

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