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Although semaglutide is considered safe for most patients, rare but serious side effects can occur, including gastroparesis or pancreatitis
Most published data comes from animal and laboratory studies, and human clinical trials are lacking, so human efficacy is not established [1]
Moderate alcohol is not prohibited, but it can worsen stomach side effects
Professor Holsts great scientific achievements include the discovery of GLP-1 (glucagon-like peptide 1) a gut hormone regulating insulin secretion and appetite and food intake and his subsequent both basic and translational research in this field
GLP-1 produced in the gut sends signals to the brain, influencing various functions, including mood regulation