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Clinical trials of VNS in obesity related diseases Multiple neuromodulation clinical trials for obesity and obesity related conditions have been conducted (Table 1)

GBD 2016 Parkinsons Disease Collaborators Global, regional, and national burden of Parkinsons disease, 19902016: a systematic analysis for the Global Burden of Disease Study 2016

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Firth (1993) profile penalized log likelihood approach was adopted to obtain robust parameter estimates in the presence of rare events such as the present dataset

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