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[28] After inducing the stroke through acute occlusion of the middle cerebral artery, the rats were given 30mg/kg NSI-189 orally, beginning 6 hours after the stroke induction and continuing daily for 12 weeks

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The nonoperative treatment of KOA mainly includes anti-inflammatory drugs and biologics, such as non-steroidal anti-inflammatory drugs (NSAIDs), hyaluronic acid, glucocorticoids, diacrine, and chondroitin sulfate [7]

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