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4, May 1998, pp

Notably, Magel2 -null mice were found to be hyperresponsive to setmelanotide compared to wild-type controls, indicating exogenous agonists are more effective in conditions with impaired MC agonist production and downstream signaling (81)

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Ubiquitylation modification assay 293 T cells were transfected with HA-PLVC, HA-KEAP1, and Myc-Ubiquitin or transfected with Flag-PLVC, Flag-NRF2, HA-KEAP1, and Myc-Ubiquitin (synthesized, purchased from Shanghai Ai Bosi Biological Technology Co., Ltd.) using lipofectamine 3000 (cat