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Subsequent cohorts were dosed after the dosing regimen in the preceding cohort was recommended to be safe and well tolerated based on the safety and laboratory data through at least day 15

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These include: Nausea and vomiting (very common, affecting more than 1 in 10 patients) Diarrhoea or constipation Abdominal discomfort or bloating Reduced appetite These symptoms often diminish over several weeks as the body adjusts to the medication

Burps that carry hydrogen sulfide gas from your digestive tract up through your esophagus and out of your mouth, producing a distinct smell identical to rotten eggs

She advises doctors to be proactive in monitoring the risk in GLP-1 patients, especially in postmenopausal women and men over age 50 who would already be at higher risk of bone loss due to their age

Br J Clin Pharmacol