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These numbers represent the highest weight reduction figures ever recorded in pharmaceutical weight loss trials

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Indirect comparisons through network meta-analyses conclude that SGLT2i ensure a greater protection than GLP-1RA against DKD progression [16,17,18]

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Who Stands to Benefit Most: Patient Profiles and Clinical Decision-Making Patients most likely to benefit from semaglutide's blood pressure effects are those with obesity (BMI 30), hypertension, and either type 2 diabetes or prediabetes

They can appear anywhere on the body, including the palms, soles, and mucosal surfaces