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In agreement with the noncompetitive behavior of 9 and as determined by structural superposition of the cryo-EM structure and the X-ray NADPH-TGR- complex 17 , inhibitor 9 does not sterically interfere with NADPH binding

PMCID: PMC11857380

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Peroxisomal -Oxidation Reactions -Oxidation Reactions In addition to mitochondrial oxidation of fatty acids, the peroxisomes play an important role in overall fatty acid metabolism