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However, limited published efficacy data and variable skin absorption remain significant challenges

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This allows glucagons effects on energy expenditure and lipid oxidation to become therapeutically useful while reducing its hyperglycemic liability

With 1:1 ratio of two N-sulfonated isomers was obtained using sodium hydride (NaH) & methanesulfonyl chloride (MsCl) for sulphonation of 13, necessitating chromatographic purifications [43]

Calculating the number needed to treat for trials where the outcome is time to an event