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Importantly, AngII triggered a transient increase in I sc in all colonic epithelial preparations in which the submucosal layer had been removed (5/5, Fig

Prepared receptor models were then processed in System Builder to define the simulation environment, assign default physiological ionization conditions, and were then subjected to a final restrained minimization to remove steric clashes and ensure structural relaxation before virtual screening calculations

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Recognition sequence of a highly conserved DNA binding protein RBP-Jx