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doi: 10.1038/s41419-021-03996-y 153 LedermannJHarterPGourleyCFriedlanderMVergoteIRustinGet al

Mechanism of Action: IGF-1 LR3 vs IGF-1 DES Both IGF-1 LR3 and IGF-1 DES bind to the IGF-1 receptor , triggering powerful anabolic pathwaysprimarily PI3K/Akt/mTOR for muscle protein synthesis and MAPK for cell proliferation

While BPC-157 excels at local tissue repair and angiogenesis, TB-500 provides superior systemic inflammation reduction and promotes cell migration to injury sites through different mechanisms

Diabetologia 52 , 15661578 (2009)

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