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Some demand documentation of failed prior weight loss attempts, including supervised diet programs or other medications like phentermine , before approving GLP-1 coverage regardless of BMI

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Careful storage supports reliable injection preparation for patient safety

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Adiponectin also decreases hepatic de novo glucose production and reduces free fatty acid levels in the liver (196), thereby mitigating hepatic steatosis, enhancing insulin sensitivity, and improving the circulating lipid profile ( Figure 1 Section E)