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High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome

This deficiency can lead to megaloblastic anemia, where the body produces large, abnormal red blood cells that cannot function effectively, resulting in symptoms such as fatigue, weakness, and neurological issues

In folate and methionine metabolism, the increases or decreases of the enzymes in the yellow ovals are given in [11]

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Despite promising aspects, a phase II clinical trial (NCT03373422) focused on treating endometriosis was terminated due to hepatotoxicity resulting from nonspecific AKR1D1 inhibition (Rizner and Penning, 2020)

doi:10.1136/bmjopen-2016-015410