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Treatment of diet-induced obese mice systemically with a potent NNMT inhibitor significantly reduced body weight and white adipose mass, decreased adipocyte size, and lowered plasma total cholesterol levels

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10.1016/j.rmed.2015.08.008 155 Perez-VilarJ.OlsenJ

Those studies generally examined L-arginine as a separate experimental agent and did not compare arginate with acetate