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The GLP-1 fatigue guide and the GLP-1 headache guide provide broader context for these side effects across the entire class of incretin-based therapies, not just tirzepatide specifically

Weight-loss medicines were treated as lifestyle products rather than medical treatments

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More than 80 per cent of those prescribed the pill in the US had never previously used weight-loss injections, suggesting the tablets could ultimately prove even more popular than the jabs, which have already been used by more than 2.5 million Britons

A recent analysis using Mendelian randomization showed that genetically predicted homocysteine levels increased the odds of NAFLD.[ref] Related article: NAFLD genes Cardiovascular disease: To answer the question of whether a modestly elevated homocysteine level is causally associated with an increased risk of cardiovascular disease, researchers again used huge genetic data sets and Mendelian randomization to determine causality

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