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Mitochondrion 28:815 Kamei N, Yamaoka A, Fukuyama Y, Itokazu R, Takeda-Morishita M (2018) Noncovalent strategy with cell-penetrating peptides to facilitate the brain delivery of insulin through the blood-brain barrier

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Furthermore, a comparative analysis measuring the protective effect of the catechol group against lipid peroxidation caused by ferrous salts, depletion of GSH induced by diethylmaleate or by hypoxia-reoxygenation, or cell death induced by hypoxia-reoxygenation, evidenced how HTyr ethyl ether (with two OH groups) was more effective than tyrosol ethyl ether (one OH) or 3,4-di- ortho -methylidene-hydroxytyrosol ethyl ether (without free OH)

The high expression of ACMSD in the kidney and liver offers the therapeutic potential of ACMSD inhibitors, such as TES-991 and TES-1025, for renal and hepatic dysfunction

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