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2 People taking retatrutidea newer GLP-1 now in phase III trialslost an average of 24 percent of their body weight in just under a year

The medication works by slowing gastric emptying and regulating hunger signals in the brain

Washington, D.C.: National Academies Press

Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with overweight or obese body-mass-indices (BMIs) often struggle with weight management on conservative therapy

This helps reduce the chance of overlapping side effects and gives the body time to adjust