another related possibility is that proving bioequivalence for drug-device combinations to earn FDA approval may be challenging as compared to oral formulations and thus attracts fewer potential competitors
If the off-period is meant to let the GH axis return to baseline, switching to another GH secretagogue defeats the purpose entirely
Cifuentes L, Hurtado MD, Cortes TM, et al
Commonly it is administered as 500 mcg per week for 6 weeks then maintenance dose is continued which is 500mcg per 2-4 weeks, as per vets findings
Someone who tolerates and maintains 12mg will see substantially more weight loss than someone who can only tolerate 4mg
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