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Following up on their discovery, this same group of researchers tested the effects of 9-me-BC in vivo, by administering the drug intraperitoneally to rats for either 5 or 10 days, and testing their performance in the well-known spatial learning task, the radial arm maze

A solution of formalin (10%, Xinhongfu Biotechnology) was prepared, which was then diluted to a 1% concentration using normal saline

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Similarly, germ-free (GF) mice exhibited decreased IFN- and IL-17 production and increased Tregs in ocular draining lymph nodes compared to conventionally housed EAU mice (108)

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Treatment was generally well tolerated and safe