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10.1038/s41598-021-81997-9 14 BarrosT

You'll need prior authorization, which typically requires BMI 30 (or 27 with comorbidities), 6 months of documented lifestyle efforts, and possibly step therapy

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Methodologically akin to a retrospective cohort analysis, our study differs in that it emulates a target trial by prespecifying the protocol, aligning index date, and using propensity score matching to emulate randomization, thereby reducing immortal-time bias, improving transparency, and aligning real-world evidence generation with clinical trial standards

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Common types of GLP1 drugs The first GLP-1 medicine, Exenatide, was introduced in 2005