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Extending the time at a dose before stepping up is a standard, evidence-informed way to improve tolerability

Research demonstrates that: Men taking semaglutide showed higher rates of testosterone deficiency (3.83%) compared to those not taking the medication (1.7%) The medication influences GLP-1 hormone levels, which affects various metabolic processes Hormonal changes may be more pronounced during initial weight loss periods [12] Important Considerations for Hormone Function: Weight loss achieved through Wegovy may lead to positive hormonal adjustments

Duration ranges from a few hours to several days, and frequency in patient reports spans from isolated episodes to daily recurrence requiring preventive management

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Reporting suspected adverse reactions helps the MHRA monitor the ongoing safety of medicines used in the UK