Front Med (Lausanne) (2020) 7:607725
It is understood that there will be no obvious damage in the brain area in the early stage of Ca 2+ imbalance, but a series of serious and persistent Ca 2+ -dependent cytotoxicity will occur later [12]
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Also, mGluR mediated calcium signals in the dendrites of perisomatic inhibitory neurons in the dentate gyrus were enhanced by bAPs (Hainmller et al., 2014)
Within the lung tumor microenvironment, CPT1Aa master regulator of fatty acid -oxidationcooperates with macrophage-derived L-carnitine to orchestrate a dual outcome: conferring resistance to ferroptosis while simultaneously impairing the antitumor function of CD8 + T lymphocytes ( Structurally characterized by up to four BCL-2 homology (BH) domains that govern protein interactions, the BCL-2 protein family is divided into three functionally opposing categories: multi-domain pro-survival members (e.g., BCL-2, BCL-XL, MCL-1), which inhibit apoptosis by sequestering BH3-only initiators (such as BIM, PUMA) and multi-domain effectors (BAX/BAK)
J Neurochem 2004