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Pregnant or breastfeeding women Individuals with a history of medullary thyroid carcinoma (MTC) Patients with multiple endocrine neoplasia type 2 (MEN2) Children and adolescents Those with significant GI motility disorders (unless cleared by a physician) Possible Side Effects of Cagrilintide Cagrilintide is generally well tolerated, but may cause: Nausea (dose-related) Decreased appetite Mild headache or fatigue GI side effects often resolve with slow dose titration

Of the 68 studies included in this general review of nicotinamide-based antioxidants, only 39 (57%) assessed study outcomes in both sexes, and only 9 (13%) reported statistical analysis related to sex differences (Supplementary Table S2)

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The individual study effect sizes were then entered into a random effects meta-analytic model using restricted maximum likelihood estimation

In the context of the lungs, alpha-tocopherol has been most commonly studied as an inhibitor of allergic inflammation in allergies and asthma [86]

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