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It important to not titrate your dose too quickly and only increase the dose if side effects are manageable and you are not noticing appetite suppression on the current dose

Conversely, if your FTO variant is associated with higher baseline metabolic demand, you might benefit from a slightly higher starting dose

While GLP-1 medications may reduce appetite and caloric intake, they can also lead to a reduction in overall protein consumption, which is vital for muscle maintenance and growth

Third, if prescribing a GLP1 RA, monitor response holistically

The results were striking

J Alzheimers Dis Rep 9: 25424823251342182