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All of the OTC enzymes discussed in this sectionlactase, alpha-galactosidase, xylose isomerase, inulinase, and fructan hydrolaseare generally recognized as safe per the FDA.29 Celiac Disease Celiac disease is an autoimmune disease in which an autoimmune response to gluten causes small intestinal inflammation and damage and symptoms such as diarrhea, constipation, abdominal pain, fatigue, nutrient deficiencies, and chronic headaches

Table S3

NAD+ Side Effects & Safety Commonly reported with SubQ Injection-site stinging, burning, redness, or temporary nodules managed with slow injection and site rotation

But overall, the dominant pattern seems to be daily administration

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The link between semaglutide and diarrhea Research indicates that while Ozempic does cause diarrhea, this side effect is often mild and manageable