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In August 2025, Eli Lilly announced that its experimental oral GLP-1 orforglipron achieved better weight loss and blood sugar control than oral semaglutide in a head-to-head late-stage trial

She added she was "so skinny" but felt so ill that she couldn't throw a ball with her son

Adv Ther 40:51025114 Candido R, Gaiotti S, Giudici F, Toffoli B, De Luca F, Velardi V, Petrucco A, Gottardi C, Manca E, Buda I, Fabris B, Bernardi S (2023) Real-world retrospective study into the effects of oral semaglutide (as a switchover or add-on therapy) in type 2 diabetes